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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316170
Species: Homo sapiens
RGD Object: Gene
Symbol: COL4A1
Name: collagen type IV alpha 1 chain
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COL4A1increases expressionISOCol4a1 (Rattus norvegicus)6480464CTDGlucose results in increased expression of COL4A1 mRNAPMID:18682491 PMID:28700904
COL4A1increases expressionISOCol4a1 (Mus musculus)6480464CTDGlucose results in increased expression of COL4A1 mRNAPMID:33270355
COL4A1multiple interactionsISOCol4a1 (Rattus norvegicus)6480464CTD[eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Enalapril inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; eplerenone inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]PMID:18682491 PMID:28700904
COL4A1multiple interactionsISOCol4a1 (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]PMID:33270355
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