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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:17620
Term: ferulic acid
Definition: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
Chemical ID: MESH:C004999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsISORELA (Homo sapiens)6480464CTD[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased localization of RELA protein]PMID:26270818
Relamultiple interactionsISORela (Mus musculus)6480464CTDferulic acid inhibits the reaction [Carbon Tetrachloride results in increased activity of and results in increased localization of RELA protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]PMID:21291945 PMID:33140555
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