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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:17620
Term: ferulic acid
Definition: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
Chemical ID: MESH:C004999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXmultiple interactionsISOBax (Rattus norvegicus)6480464CTDferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]PMID:31029786 PMID:35110471
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