GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | increases expression | EXP | | 6480464 | CTD | hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein | PMID:21059386 PMID:28645578 PMID:29508652 PMID:31256213 PMID:32141582 PMID:32334435 PMID:32818234 PMID:36646296 | HMOX1 | multiple interactions | EXP | | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; [Resveratrol co-treated with hydroquinone] results in increased expression of HMOX1 protein; ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; Resveratrol promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein] | PMID:21059386 PMID:28645578 PMID:32141582 PMID:32334435 PMID:32818234 PMID:36646296 | HMOX1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein | PMID:17464197 PMID:23290930 PMID:30547568 | HMOX1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; AG 1879 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; bisindolylmaleimide I inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Cysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein] | PMID:23290930 | | ||||||||||||||||||||||
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