GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | affects localization | ISO | JUN (Homo sapiens) | 6480464 | CTD | hydroquinone affects the localization of JUN protein | PMID:26807887 | Jun | increases phosphorylation | ISO | JUN (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased phosphorylation of JUN protein | PMID:23288922 PMID:23791922 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein] | PMID:23288922 PMID:23791922 | | ||||||||||||||||||||||
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