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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11250
Species: Mus musculus
RGD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:17579
Term: beta-carotene
Definition: A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid.
Chemical ID: MESH:D019207
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rxramultiple interactionsISORXRA (Homo sapiens)6480464CTDbeta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]PMID:16632523
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