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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:17579
Term: beta-carotene
Definition: A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid.
Chemical ID: MESH:D019207
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:692136480464CTDbeta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein], beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein]

PMID:17051425
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.