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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731027
Species: Homo sapiens
RGD Object: Gene
Symbol: BDNF
Name: brain derived neurotrophic factor
Acc ID: CHEBI:17578
Term: toluene
Definition: The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
Chemical ID: MESH:D014050
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BDNFdecreases expressionISOBdnf (Mus musculus)6480464CTDToluene results in decreased expression of BDNF mRNAPMID:17481687
BDNFincreases expressionISOBdnf (Mus musculus)6480464CTDToluene results in increased expression of BDNF mRNAPMID:17870172 PMID:19932712 PMID:21381054
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