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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2623
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fmr1
Name: fragile X messenger ribonucleoprotein 1
Acc ID: CHEBI:17578
Term: toluene
Definition: The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
Chemical ID: MESH:D014050
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fmr1multiple interactionsISOFMR1 (Homo sapiens)6480464CTD[Toluene co-treated with Xylenes co-treated with ethylbenzene] results in decreased expression of FMR1 mRNA; [Toluene co-treated with Xylenes co-treated with ethylbenzene] results in increased methylation of FMR1 gene; [Toluene co-treated with Xylenes] results in decreased expression of FMR1 mRNA; [Toluene co-treated with Xylenes] results in increased methylation of FMR1 genePMID:33438815
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