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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1342656
Species: Homo sapiens
RGD Object: Gene
Symbol: KLF4
Name: KLF transcription factor 4
Acc ID: CHEBI:17578
Term: toluene
Definition: The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
Chemical ID: MESH:D014050
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KLF4multiple interactionsEXP 6480464CTD[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of KLF4 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of KLF4 genePMID:26018793
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