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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553186
Species: Mus musculus
RGD Object: Gene
Symbol: Wdr74
Name: WD repeat domain 74
Acc ID: CHEBI:17574
Term: biochanin A
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at position 5 and a methoxy group at position 4'. A phytoestrogen, it has putative benefits in dietary cancer prophylaxis.
Chemical ID: MESH:C004541
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wdr74decreases expressionISORGD:16033956480464CTDbiochanin A results in decreased expression of WDR74 mRNA

PMID:12111696
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.