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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:175715
Term: 3-O-Caffeoyl-1-O-methylquinic acid
Definition: null
Chemical ID: MESH:C490257
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTD3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA; 3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 proteinPMID:16631525
Hmox1multiple interactionsISOHMOX1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; pyrazolanthrone inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 protein]PMID:16631525
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