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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3285
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdgfrb
Name: platelet derived growth factor receptor beta
Acc ID: CHEBI:17561
Term: L-cysteine
Definition: An optically active form of cysteine having L-configuration.
Chemical ID: MESH:D003545
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfrbdecreases expressionEXP 6480464CTDCysteine results in decreased expression of PDGFRB proteinPMID:15158331
Pdgfrbmultiple interactionsEXP 6480464CTDCysteine inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; Cysteine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]PMID:15158331
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