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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2904
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il7
Name: interleukin 7
Acc ID: CHEBI:17509
Term: 5'-S-methyl-5'-thioadenosine
Definition: Adenosine with the hydroxy group at C-5' substituted with a methylthio (methylsulfanyl) group.
Chemical ID: MESH:C008500
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il7multiple interactionsISOIL7 (Homo sapiens)6480464CTDIL7 protein inhibits the reaction [5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein]PMID:31712395
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