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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735631
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP11A1
Name: cytochrome P450 family 11 subfamily A member 1
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCyclic AMP results in increased expression of CYP11A1 mRNA, Cyclic AMP results in increased expression of CYP11A1 protein

PMID:29228121
increases expressionISORGD:7356326480464CTDCyclic AMP results in increased expression of CYP11A1 mRNA

PMID:25576683, PMID:28668616
multiple interactionsISORGD:7356326480464CTDmyricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA], quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA], Quercetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]

PMID:28668616
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.