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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314176
Species: Homo sapiens
RGD Object: Gene
Symbol: CARM1
Name: coactivator associated arginine methyltransferase 1
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CARM1increases phosphorylationEXP 6480464CTDCyclic AMP results in increased phosphorylation of CARM1 proteinPMID:20360387
CARM1multiple interactionsEXP 6480464CTD[Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased expression of TFF1 mRNA]; Cyclic AMP promotes the reaction [CARM1 protein binds to ESR1 protein]; Cyclic AMP promotes the reaction [CARM1 protein binds to TFF1 promoter]PMID:20360387
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