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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10111
Species: Mus musculus
RGD Object: Gene
Symbol: Grk2
Name: G protein-coupled receptor kinase 2
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grk2multiple interactionsISOGRK2 (Homo sapiens)6480464CTD[[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein]PMID:25191754
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