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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10438
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:17484
Term: benzyl isothiocyanate
Definition: An isothiocyanate that has formula C8H7NS.
Chemical ID: MESH:C031403
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2increases expressionISOCyp1a2 (Rattus norvegicus)6480464CTDbenzyl isothiocyanate results in increased expression of CYP1A2 mRNAPMID:22664424
Cyp1a2multiple interactionsISOCyp1a2 (Rattus norvegicus)6480464CTDbenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]PMID:22664424
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