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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Acc ID: CHEBI:174748
Term: C.I. Natural Red 20
Definition: null
Chemical ID: MESH:C016101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageISOPARP1 (Homo sapiens)6480464CTDshikonin results in increased cleavage of PARP1 proteinPMID:24463199 PMID:37268198
Parp1multiple interactionsISOPARP1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein]PMID:24463199
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