GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc22a8 | affects transport | EXP | | 6480464 | CTD | SLC22A8 protein affects the transport of estrone sulfate | PMID:16079298 | Slc22a8 | increases import | EXP | | 6480464 | CTD | SLC22A8 protein results in increased import of estrone sulfate | PMID:19915082 | Slc22a8 | increases uptake | EXP | | 6480464 | CTD | SLC22A8 protein results in increased uptake of estrone sulfate | PMID:10224140 PMID:16857889 | Slc22a8 | multiple interactions | EXP | | 6480464 | CTD | 3,4-dihydroxymandelic acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; 3,4-Dihydroxyphenylacetic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; 5-methoxyindoleacetic acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Bumetanide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Furosemide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; hexadecafluoro-nonanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; Homovanillic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Indocyanine Green inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; methoxytryptophol inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; perfluoro-n-heptanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; perfluorodecanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; perfluorooctanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; Piroxicam inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Sulfobromophthalein inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Vanilmandelic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] | PMID:10224140 PMID:15319347 PMID:19915082 | Slc22a8 | affects transport | ISO | SLC22A8 (Homo sapiens) | 6480464 | CTD | SLC22A8 protein affects the transport of estrone sulfate | PMID:11306713 PMID:15496291 | Slc22a8 | increases import | ISO | SLC22A8 (Homo sapiens) | 6480464 | CTD | SLC22A8 protein results in increased import of estrone sulfate | PMID:28629854 | Slc22a8 | increases uptake | ISO | SLC22A8 (Homo sapiens) | 6480464 | CTD | SLC22A8 protein results in increased uptake of estrone sulfate; SLC22A8 results in increased uptake of estrone sulfate | PMID:16098483 PMID:16857889 PMID:17255469 PMID:19605544 PMID:19643159 PMID:21256917 PMID:27989701 PMID:28890383 PMID:32003934 PMID:32305507 | Slc22a8 | increases uptake | ISO | Slc22a8 (Mus musculus) | 6480464 | CTD | SLC22A8 protein results in increased uptake of estrone sulfate | PMID:15100168 | Slc22a8 | multiple interactions | ISO | SLC22A8 (Homo sapiens) | 6480464 | CTD | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; aristolochic acid I inhibits the reaction [SLC22A8 results in increased uptake of estrone sulfate]; bisphenol A inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; bisphenol F inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; bisphenol S inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Bumetanide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Cefaclor inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Cefdinir inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; cefoselis inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Cefotiam inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Ceftibuten inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Ceftizoxime inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Cephaloridine inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Cholates inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Cimetidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Dehydroepiandrosterone inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Diclofenac inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; estrone sulfate promotes the reaction [SLC22A8 results in increased export of p-Aminohippuric Acid]; Famotidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Furosemide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Ibuprofen inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Indomethacin inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Quercetin inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; rhein inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; rhein metabolite inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; tetrabromobisphenol A inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Tobacco Smoke Pollution inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] | PMID:11306713 PMID:15496291 PMID:16098483 PMID:19605544 PMID:19643159 PMID:27989701 PMID:28629854 PMID:28890383 PMID:32003934 PMID:32305507 | | ||||||||||||||||||||||
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