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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730853
Species: Homo sapiens
RGD Object: Gene
Symbol: GAD1
Name: glutamate decarboxylase 1
Acc ID: CHEBI:174690
Term: clenbuterol
Definition: A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.
Chemical ID: MESH:D002976
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GAD1multiple interactionsISOGad1 (Rattus norvegicus)6480464CTDClenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]; Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA]; Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]]PMID:8774452
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