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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733281
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC22A4
Name: solute carrier family 22 member 4
Acc ID: CHEBI:17456
Term: dithioerythritol
Definition: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol.
Chemical ID: MESH:D004226
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC22A4multiple interactionsEXP 6480464CTDDithioerythritol inhibits the reaction [Cadmium results in decreased activity of SLC22A4 protein]; Dithioerythritol inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Dithioerythritol inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein]PMID:25490951
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