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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:17447
Term: geraniol
Definition: A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end.
Chemical ID: MESH:C007836
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiamultiple interactionsEXP 6480464CTDgeraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845
Nfkbiamultiple interactionsISONfkbia (Rattus norvegicus)6480464CTDgeraniol inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of NFKBIA protein]PMID:34343525
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