Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1352582
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	IL6
Name:	interleukin 6

Acc ID:	CHEBI:174232
Term:	4'-Methoxychalcone
Definition:	null
Chemical ID:	MESH:C097470

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
IL6	multiple interactions	ISO	Il6 (Mus musculus)	6480464	CTD	4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]	PMID:28528971

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.