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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308277
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1b10
Name: aldo-keto reductase family 1 member B10
Acc ID: CHEBI:17378
Term: D-glyceraldehyde
Definition: The D-enantiomer of glyceraldehyde.
Chemical ID: MESH:D005985
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b10increases metabolic processingISORGD:13179596480464CTDAKR1B10 protein results in increased metabolism of Glyceraldehyde

PMID:18325492
Akr1b10increases reductionISORGD:13179596480464CTDAKR1B10 protein results in increased reduction of Glyceraldehyde

PMID:19014918 PMID:19028477
Akr1b10multiple interactionsISORGD:13179596480464CTD[AKR1B10 protein co-treated with NADP] affects the reduction of Glyceraldehyde ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] ethyl 1-benzyl-3-hydroxy-25H-oxopyrrole-4-carboxylate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] pirinixic acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]

PMID:17329238 PMID:19028477
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