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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305285
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Postn
Name: periostin
Acc ID: CHEBI:173719
Term: Curcumol
Definition: null
Chemical ID: MESH:C022801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Postndecreases expressionISOPOSTN (Homo sapiens)6480464CTDcurcumol results in decreased expression of POSTN mRNAPMID:32344006
Postnmultiple interactionsISOPOSTN (Homo sapiens)6480464CTDcurcumol results in decreased expression of and results in decreased secretion of POSTN protein; POSTN protein affects the reaction [curcumol results in decreased expression of ICAM1 protein]; POSTN protein affects the reaction [curcumol results in decreased expression of VCAM1 protein]PMID:32344006
Postnmultiple interactionsISOPostn (Mus musculus)6480464CTDcurcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of POSTN protein]PMID:32344006
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