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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323543
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC22A12
Name: solute carrier family 22 member 12
Acc ID: CHEBI:17368
Term: hypoxanthine
Definition: A purine nucleobase that consists of purine bearing an oxo substituent at position 6.
Chemical ID: MESH:D019271
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC22A12multiple interactionsISOSlc22a12 (Mus musculus)6480464CTD[Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 mRNA; [Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 protein; Allopurinol inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 mRNA]; Allopurinol inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 protein]; Polysaccharides inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 mRNA]; Polysaccharides inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in increased expression of SLC22A12 protein]PMID:34687833
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