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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735865
Species: Homo sapiens
RGD Object: Gene
Symbol: ANXA3
Name: annexin A3
Acc ID: CHEBI:17356
Term: 2-acetamidofluorene
Definition: The parent of the class of 2-acetamidofluorenes, being an ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene.
Chemical ID: MESH:D015073
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ANXA3increases expressionISOAnxa3 (Mus musculus)6480464CTD2-Acetylaminofluorene results in increased expression of ANXA3 mRNAPMID:17317680
ANXA3multiple interactionsISOAnxa3 (Rattus norvegicus)6480464CTD[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of ANXA3 mRNAPMID:18071240
ANXA3multiple interactionsISOAnxa3 (Mus musculus)6480464CTDTRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ANXA3 mRNA]PMID:17317680
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