GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EGF | decreases expression | EXP | | 6480464 | CTD | Testosterone results in decreased expression of EGF mRNA | PMID:33359661 | EGF | increases expression | EXP | | 6480464 | CTD | Testosterone results in increased expression of EGF mRNA | PMID:21592394 | EGF | multiple interactions | EXP | | 6480464 | CTD | [Testosterone co-treated with Calcitriol] results in increased expression of EGF mRNA | PMID:21592394 | EGF | decreases secretion | ISO | Egf (Rattus norvegicus) | 6480464 | CTD | EGF protein results in decreased secretion of Testosterone | PMID:19059320 | EGF | increases expression | ISO | Egf (Rattus norvegicus) | 6480464 | CTD | Testosterone results in increased expression of EGF protein | PMID:27866977 | EGF | multiple interactions | ISO | Egf (Rattus norvegicus) | 6480464 | CTD | EGF protein inhibits the reaction [AG 1879 inhibits the reaction [Testosterone results in increased phosphorylation of CREB1 protein]]; EGF protein inhibits the reaction [AG 1879 inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]; EGF protein inhibits the reaction [AG 1879 inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]; Finasteride inhibits the reaction [Testosterone results in increased expression of EGF protein]; Qing Ye Dan inhibits the reaction [Testosterone results in increased expression of EGF protein]; swertiamarin inhibits the reaction [Testosterone results in increased expression of EGF protein] | PMID:17272394 PMID:27866977 | | ||||||||||||||||||||||
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