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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70988
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akap12
Name: A-kinase anchoring protein 12
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akap12increases expressionISOAKAP12 (Homo sapiens)6480464CTDTestosterone results in increased expression of AKAP12 mRNAPMID:21592394
Akap12multiple interactionsISOAKAP12 (Homo sapiens)6480464CTD[FSHB protein co-treated with Testosterone] results in decreased expression of AKAP12 mRNA; [Testosterone co-treated with Calcitriol] results in increased expression of AKAP12 mRNAPMID:18535249 PMID:21592394
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