GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Top2a | increases expression | EXP | | 6480464 | CTD | Testosterone results in increased expression of TOP2A mRNA | PMID:19693291 | Top2a | decreases expression | ISO | TOP2A (Homo sapiens) | 6480464 | CTD | Testosterone results in decreased expression of TOP2A mRNA | PMID:21592394 | Top2a | multiple interactions | ISO | TOP2A (Homo sapiens) | 6480464 | CTD | [Testosterone co-treated with Calcitriol] results in decreased expression of TOP2A mRNA | PMID:21592394 | Top2a | multiple interactions | ISO | Top2a (Rattus norvegicus) | 6480464 | CTD | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TOP2A mRNA | PMID:32741896 | |
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