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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620288
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Calr
Name: calreticulin
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Calraffects expressionISOCalr (Mus musculus)6480464CTDTestosterone affects the expression of CALR mRNAPMID:17003280
Calrdecreases expressionISOCalr (Mus musculus)6480464CTDTestosterone deficiency results in decreased expression of CALR mRNAPMID:33848595
Calrincreases expressionISOCALR (Homo sapiens)6480464CTDTestosterone results in increased expression of CALR mRNAPMID:20564326
Calrmultiple interactionsISOCALR (Homo sapiens)6480464CTDdutasteride promotes the reaction [Testosterone results in increased expression of CALR mRNA]PMID:20564326
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