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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pparg
Name: peroxisome proliferator-activated receptor gamma
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargdecreases expressionISOPPARG (Homo sapiens)6480464CTDTestosterone results in decreased expression of PPARG mRNAPMID:21632903 PMID:33359661
Ppargdecreases expressionISOPparg (Mus musculus)6480464CTDTestosterone results in decreased expression of PPARG mRNA; Testosterone results in decreased expression of PPARG proteinPMID:12960001 PMID:20844152
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