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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3115
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mstn
Name: myostatin
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mstndecreases expressionEXP 6480464CTDTestosterone results in decreased expression of MSTN mRNA; Testosterone results in decreased expression of MSTN proteinPMID:17658471
Mstndecreases expressionISOMstn (Mus musculus)6480464CTDTestosterone deficiency results in decreased expression of MSTN mRNAPMID:21045173
Mstnmultiple interactionsISOMstn (Mus musculus)6480464CTDTestosterone inhibits the reaction [Testosterone deficiency results in decreased expression of MSTN mRNA]PMID:21045173
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