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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559459
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RGD1559459
Name: similar to Expressed sequence AI788959
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of RGD1559459 mRNA

PMID:26496021
increases expressionISORGD:13491656480464CTDTestosterone results in increased expression of UGT2B28 mRNA

PMID:31393563
multiple interactionsISORGD:13491656480464CTDalpha-terpineol inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], Flutamide inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], lavender oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], linalool inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA], terpinenol-4 inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]

PMID:31393563
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.