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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases expressionISOParp1 (Rattus norvegicus)6480464CTDTestosterone results in increased expression of PARP1 proteinPMID:25714330
Parp1multiple interactionsISOParp1 (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Testosterone results in increased expression of PARP1 protein]PMID:25714330
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