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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318014
Species: Homo sapiens
RGD Object: Gene
Symbol: NLRP3
Name: NLR family pyrin domain containing 3
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NLRP3increases expressionEXP 6480464CTDTestosterone results in increased expression of NLRP3 mRNAPMID:33359661
NLRP3multiple interactionsISONlrp3 (Rattus norvegicus)6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of NLRP3 mRNAPMID:32741896
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