An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID:
MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Testosterone deficiency results in increased expression of AR mRNA; Testosterone results in increased expression of AR mRNA; Testosterone results in increased expression of AR protein
[Testosterone binds to AR protein] which binds to KLK2 promoter; [Testosterone binds to AR protein] which binds to KLK3 promoter; Testosterone binds to AR protein
[Metoclopramide results in decreased abundance of Testosterone] which results in decreased expression of AR protein; [Testosterone binds to AR protein] inhibits the reaction [Dexamethasone results in increased expression of DDIT4 mRNA]; AR affects the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]; AR affects the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]; AR mutant form inhibits the reaction [Testosterone results in increased expression of CYP11A1 protein]; AR mutant form inhibits the reaction [Testosterone results in increased expression of CYP19A1 protein]; AR mutant form inhibits the reaction [Testosterone results in increased expression of NR5A2 mRNA]; bicalutamide inhibits the reaction [[Testosterone binds to AR protein] inhibits the reaction [Dexamethasone results in increased expression of DDIT4 mRNA]]; bisphenol A inhibits the reaction [Testosterone affects the localization of and results in increased activity of AR protein]; dapoxetine inhibits the reaction [Testosterone results in increased expression of AR mRNA]; Finasteride inhibits the reaction [Testosterone results in increased expression of AR mRNA]; Finasteride inhibits the reaction [Testosterone results in increased expression of AR protein]; Flutamide inhibits the reaction [Testosterone results in increased activity of AR protein]; Flutamide inhibits the reaction [Testosterone results in increased expression of AR mRNA]; Fulvestrant inhibits the reaction [Testosterone results in increased expression of AR mRNA]; Plant Extracts inhibits the reaction [Testosterone results in increased activity of AR protein]; Qing Ye Dan inhibits the reaction [Testosterone results in increased expression of AR protein]; RNF4 protein promotes the reaction [Testosterone promotes the reaction [AR protein results in increased expression of PBSN mRNA]]; RNF4 protein promotes the reaction [Testosterone results in increased activity of AR protein]; Silymarin inhibits the reaction [Testosterone results in increased expression of AR protein]; swertiamarin inhibits the reaction [Testosterone results in increased expression of AR protein]; Testosterone affects the localization of and results in increased activity of AR protein; Testosterone affects the reaction [AR protein results in increased expression of AR mRNA]; Testosterone promotes the reaction [AR protein results in increased expression of PBSN mRNA]; Testosterone promotes the reaction [RNF4 protein binds to and results in increased activity of AR protein]; Testosterone promotes the reaction [SRC protein binds to AR protein]; Triclosan inhibits the reaction [Testosterone binds to AR protein]; vinclozolin inhibits the reaction [Testosterone affects the localization of and results in increased activity of AR protein]
1,1-bis(4-hydroxyphenyl)cyclohexane inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [methoxyacetic acid promotes the reaction [Testosterone results in increased activity of AR protein]]; 4,4'-bisphenol F inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; 4,4'-bisphenol F inhibits the reaction [Testosterone results in increased activity of AR protein]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Testosterone results in increased expression of AR mRNA]; [AR mutant form co-treated with Testosterone] affects the expression of TSC1 protein; [AR mutant form co-treated with Testosterone] results in increased expression of TSC2 protein; [bicalutamide co-treated with Testosterone] affects the expression of and results in decreased activity of AR protein; [Calcitriol co-treated with Testosterone] results in increased expression of AR mRNA; [Calcitriol co-treated with Testosterone] results in increased expression of AR protein; [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [AR protein binds to TRAF6 protein]; AR mutant form inhibits the reaction [Testosterone affects the phosphorylation of EIF4BP1 protein]; AR mutant form inhibits the reaction [Testosterone results in increased expression of KLK2 protein]; AR mutant form inhibits the reaction [Testosterone results in increased phosphorylation of RPS6 protein]; AR mutant form inhibits the reaction [Testosterone results in increased phosphorylation of RPS6KB1 protein]; Benzo(a)pyrene inhibits the reaction [Testosterone results in increased expression of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of AR mRNA]; bicalutamide affects the reaction [Testosterone affects the expression of AR protein]; bicalutamide inhibits the reaction [Testosterone results in increased activity of AR protein]; bisphenol A inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; bisphenol A inhibits the reaction [Testosterone results in increased activity of AR protein]; bisphenol B inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; bisphenol S inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [Testosterone results in increased activity of AR protein]; Flutamide inhibits the reaction [Testosterone results in increased expression of AR mRNA]; gamma-terpinene inhibits the reaction [Testosterone results in increased activity of AR protein]; ginsenoside Rg3 inhibits the reaction [Testosterone results in increased expression of AR protein]; hydroxyflutamide inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Testosterone results in increased phosphorylation of AR protein]; lavender oil inhibits the reaction [Testosterone results in increased activity of AR protein]; linalool inhibits the reaction [Testosterone results in increased activity of AR protein]; linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein]; Linuron inhibits the reaction [Testosterone results in increased activity of AR protein]; methoxyacetic acid inhibits the reaction [bicalutamide inhibits the reaction [Testosterone results in increased activity of AR protein]]; methoxyacetic acid inhibits the reaction [Linuron inhibits the reaction [Testosterone results in increased activity of AR protein]]; methoxyacetic acid inhibits the reaction [vinclozolin inhibits the reaction [Testosterone results in increased activity of AR protein]]; methoxyacetic acid promotes the reaction [Testosterone results in increased activity of AR protein]; Particulate Matter analog inhibits the reaction [Testosterone binds to AR protein]; Plant Extracts inhibits the reaction [Testosterone binds to AR protein]; Polyphenols inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR protein]; Sirolimus affects the reaction [Testosterone results in increased expression of AR protein]; Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein]; Testosterone affects the localization of and results in increased activity of AR protein; Testosterone binds to and results in increased activity of AR protein; Testosterone inhibits the reaction [Dihydrotestosterone binds to AR protein]; Testosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; tetrabromobisphenol A inhibits the reaction [Testosterone results in increased activity of AR protein]; triclocarban analog promotes the reaction [Testosterone results in increased activity of AR protein]; triclocarban promotes the reaction [Testosterone results in increased activity of AR protein]; tyrphostin A23 inhibits the reaction [methoxyacetic acid promotes the reaction [Testosterone results in increased activity of AR protein]]; Vehicle Emissions analog inhibits the reaction [Testosterone binds to AR protein]; vinclozolin inhibits the reaction [Testosterone results in increased activity of AR protein]; zearalenol inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; Zearalenone inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]
