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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735252
Species: Mus musculus
RGD Object: Gene
Symbol: Rbp4
Name: retinol binding protein 4, plasma
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rbp4decreases secretionEXP 6480464CTDVitamin A deficiency results in decreased secretion of RBP4 proteinPMID:22001960
Rbp4increases secretionEXP 6480464CTDVitamin A results in increased secretion of RBP4 proteinPMID:22001960
Rbp4multiple interactionsEXP 6480464CTDVitamin A results in decreased expression of and results in decreased secretion of RBP4 proteinPMID:22542753
Rbp4affects bindingISORBP4 (Homo sapiens)6480464CTDVitamin A binds to RBP4 proteinPMID:16461020 PMID:16762690 PMID:18316031
Rbp4multiple interactionsISORBP4 (Homo sapiens)6480464CTDFenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]; Vitamin A results in decreased expression of and results in decreased secretion of RBP4 proteinPMID:21591606 PMID:22542753
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