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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349499
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT1A6
Name: UDP glucuronosyltransferase family 1 member A6
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT1A6decreases expressionISOUgt1a6 (Rattus norvegicus)6480464CTDVitamin A deficiency results in decreased expression of UGT1A6 mRNAPMID:12163651
UGT1A6multiple interactionsISOUgt1a6 (Rattus norvegicus)6480464CTDVitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA]PMID:11299074
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