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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:17301
Term: glucaric acid
Definition: A hexaric acid derived by oxidation of sugar such as glucose with nitric acid.
Chemical ID: MESH:D005937
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsISORGD:7310076480464CTD[resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9 10-Dimethyl-1 2-benzanthracene] results in increased expression of PTGS2 mRNA] [ursolic acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9 10-Dimethyl-1 2-benzanthracene] results in increased expression of PTGS2 mRNA] Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9 10-Dimethyl-1 2-benzanthracene] results in increased expression of PTGS2 mRNA]

PMID:23835587
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