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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:17301
Term: glucaric acid
Definition: A hexaric acid derived by oxidation of sugar such as glucose with nitric acid.
Chemical ID: MESH:D005937
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1multiple interactionsISORGD:104396480464CTD[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in increased expression of CYP1B1 mRNA] [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in increased expression of CYP1B1 mRNA]

PMID:20103723
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