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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:17301
Term: glucaric acid
Definition: A hexaric acid derived by oxidation of sugar such as glucose with nitric acid.
Chemical ID: MESH:D005937
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:102896480464CTD[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased activity of CASP3 protein] [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased expression of CASP3 mRNA] [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased expression of CASP3 protein] Glucaric Acid inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased activity of CASP3 protein] Glucaric Acid inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased expression of CASP3 mRNA] Glucaric Acid inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in decreased expression of CASP3 protein]

PMID:25478867
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