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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737309
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARA
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:17300
Term: tetrachloroethene
Definition: A chlorocarbon that is tetrachloro substituted ethene.
Chemical ID: MESH:D013750
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARAincreases activityEXP 6480464CTDTetrachloroethylene metabolite results in increased activity of PPARA proteinPMID:10581215
PPARAincreases activityISOPpara (Mus musculus)6480464CTDTetrachloroethylene metabolite results in increased activity of PPARA proteinPMID:10581215
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