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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708367
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b12
Name: hydroxysteroid (17-beta) dehydrogenase 12
Acc ID: CHEBI:17263
Term: estrone
Definition: A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17.
Chemical ID: MESH:D004970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b12increases metabolic processingISOHSD17B12 (Homo sapiens)6480464CTDHSD17B12 protein results in increased metabolism of EstronePMID:16166196
Hsd17b12increases metabolic processingISOHsd17b12 (Mus musculus)6480464CTDHSD17B12 protein results in increased metabolism of EstronePMID:17641292
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