GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | affects expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA | PMID:33631300 | Mmp9 | decreases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein | PMID:28416457 | Mmp9 | increases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein | PMID:28390675 PMID:33631300 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | 2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein]; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; mifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein] | PMID:28390675 PMID:28416457 PMID:30398665 PMID:33631300 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA] | PMID:29718165 | | ||||||||||||||||||||||
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