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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1615200
Species: Mus musculus
RGD Object: Gene
Symbol: Fasn
Name: fatty acid synthase
Acc ID: CHEBI:17243
Term: mono(2-ethylhexyl) phthalate
Definition: The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C016599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasndecreases expressionEXP 6480464CTDmono-(2-ethylhexyl)phthalate results in decreased expression of FASN mRNAPMID:25543134
Fasnincreases expressionEXP 6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of FASN proteinPMID:27384973
Fasnmultiple interactionsEXP 6480464CTD[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of FASN mRNAPMID:27181934
Fasnincreases expressionISOFASN (Homo sapiens)6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of FASN mRNAPMID:23118965
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