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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733801
Species: Homo sapiens
RGD Object: Gene
Symbol: MAP3K1
Name: mitogen-activated protein kinase kinase kinase 1
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAP3K1multiple interactionsEXP 6480464CTD[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to GlucosePMID:27278863
MAP3K1increases expressionISOMap3k1 (Mus musculus)6480464CTDGlucose results in increased expression of MAP3K1 mRNAPMID:24659233
MAP3K1multiple interactionsISOMap3k1 (Mus musculus)6480464CTDresveratrol inhibits the reaction [Glucose results in increased expression of MAP3K1 mRNA]PMID:24659233
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