Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731404
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKCB
Name: protein kinase C beta
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKCBincreases activityEXP 6480464CTDGlucose results in increased activity of PRKCB proteinPMID:20578705
PRKCBincreases expressionEXP 6480464CTDGlucose results in increased expression of PRKCB protein; Glucose results in increased expression of PRKCB protein alternative formPMID:16285992
PRKCBincreases phosphorylationEXP 6480464CTDGlucose results in increased phosphorylation of PRKCB proteinPMID:22162761
PRKCBmultiple interactionsEXP 6480464CTD5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of PRKCB protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of PRKCB protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of PRKCB protein]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein]; resveratrol inhibits the reaction [Glucose results in increased activity of PRKCB protein]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of PRKCB protein]PMID:16285992 PMID:20578705
PRKCBmultiple interactionsISOPrkcb (Rattus norvegicus)6480464CTDGlucose results in increased phosphorylation of and results in increased activity of PRKCB protein; PRKCB protein affects the reaction [Glucose results in increased activity of RELA protein]; PRKCB protein affects the reaction [Glucose results in increased expression of NOS2 protein]; PRKCB protein affects the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PRKCB protein affects the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ruboxistaurin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of PRKCB protein]PMID:19587355
Go Back to source page   Continue to Ontology report