GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Irs2 | decreases expression | ISO | IRS2 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of IRS2 protein; Glucose results in decreased expression of IRS2 protein modified form | PMID:24262486 | Irs2 | increases abundance | ISO | Irs2 (Mus musculus) | 6480464 | CTD | IRS2 gene mutant form results in increased abundance of Glucose | PMID:20028942 | Irs2 | increases phosphorylation | ISO | IRS2 (Homo sapiens) | 6480464 | CTD | Glucose results in increased phosphorylation of IRS2 protein | PMID:10430617 | Irs2 | multiple interactions | ISO | IRS2 (Homo sapiens) | 6480464 | CTD | Catechin inhibits the reaction [Glucose results in decreased expression of IRS2 protein modified form]; Catechin inhibits the reaction [Glucose results in decreased expression of IRS2 protein]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS2 protein modified form]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS2 protein] | PMID:24262486 | |
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